Quality of Life Associated with Health in Spinal Tuberculosis
Juan Camilo Salcedo Moreno, Pedro Aleixo Nogueira, Armando Alpizar Aguirre, Tania Arancibia Baspineiro, Julio Cesar Burgos Flores, Andrei Andrei, Eduardo Laos Plasier, Edson Lizarazu-Oroz, Carlos Antonio Llanos-Lucero, Jose Luis López Segales, Thiago Magalhaes de Souza, Juan Felipe Mier-García, Molina Pizarro, Filadelfo Norambuena, María Elizabeth Núñez Castillo, Erika Reyes Quezada, Wilson Quispe-Alanoca, Paulo Gabriel Sacramento da Silva, Byron Salazar Maldonado, Jorge Salazar Flores, Josselin-María Sanchez Mamani, Felipe Augusto Santos de Queiroz Chaves, Reddy Atilio Simon Nunes, Manuel Eduardo Soto García, Perla Maria Del Valle Oros, Jose Alberto Israel Romero Rangel, Luis Miguel Duchen Rodríguez, Jose Antonio Soriano Sanchez
Abstract
ntroduction: Spinal tuberculosis, although rare, is a variant of miliary TB, which when it occurs can lead to catastrophic injuries, since it is usually painful and disfiguring, and can lead to irreversible neurological injuries. Which directly or indirectly has an impact on the quality of life of the patient. For this reason, our objective is to review the updated literature on the impact of spinal TB on the quality of life of patients and to identify variables that are directly or indirectly associated with better or worse results. Methodology: Following the Prisma criteria for the development of the article, a search strategy and another alternative strategy are developed for the updated collection of information related to spinal TB and Quality of life between 2017-2022. Having as inclusion criterion the objective measurement, either direct or indirect, of the Quality of Life by some Scale or Standardized Measurement Instrument. Using the GRADE strategy as the risk of bias assessment, which allows us to approximate the possibilities of bias per article. While the final recommendations were supported according to the SORT criteria according to the quality of the study. Results: 45 articles were identified, and 36 articles were excluded from the search because they did not meet the temporality and/or title and abstract criteria. Therefore, 8 articles were obtained, all addressed the term Quality of Life through different Scales, the most frequent being the Visual Analogue Scale (VAS) and the Oswestry Disability Scale (ODI). However, others addressed the SF 36 Questionnaire, the Neck Disability Index (NDI), the Japanese Orthopedic Association (JOA) Scale, and the Macnab Score. Without being the quality of life the focus of discussion of these articles, but one more variable among the different variables that are influenced by the type of approach implemented and/or the material used. Discussion/Conclusion: Within our updated search we include 8 articles that allow us to recognize that today there are no articles directed to this aspect, and whose central axis of its theme covers the subject of Quality of Life in Spinal TBC, however, they warn the importance of the same for patients, as a relevant variant when evaluating clinical response. There are currently different Scales that directly or indirectly measure the individual’s Quality of Life as a result variable subject to pain control and patient functionality. With a high probability of Bias given the design of the studies and their level of evidence, the small number of samples, short follow-up periods, the possibility of selection and recall bias, among others. With a Level of Quality a Priori and a Low Posteriori according to GRADE. It is recommended to carry out studies with a design that supports better evidence to provide more solid recommendations.
Keywords
References
[1] Natalia Giraldo Gallego, Daniel Valencia Acevedo, and Jaiberth Antonio Cardona-Arias. Calidad de vida relacionada con la salud en tuberculosis: Revisi´on sistem´atica y metan´alisis. Infectio, 22(3):124–130, 2018.
[2] J. L. Brozek and et al. Grading quality of evidence and strength of recommendations in clinical practice guidelines part 3 of 3. the grade approach to developing recommendations. Allergy Eur. J. Allergy Clin. Immunol., 66:588–595, 2011.
[3] J. L. Brozek and et al. Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 2 of 3. the grade approach to grading quality of evidence about diagnostic tests and strategies. Allergy Eur. J. Allergy Clin. Immunol., 64:1109–1116, 2009.
[4] J. L. Broek and et al. Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 1 of 3. an overview of the grade approach and grading quality of evidence about interventions. Allergy Eur. J. Allergy Clin. Immunol., 64:669–677, 2009.
[5] A. Liberati and et al. The prisma statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration. BMJ, 339:1–67, 2009.
[6] A. R. K. Ebell and M. D. Ebell. Strength of recommendation taxonomy (sort). Am. Fam. Physician, 83:1227, 2011.
[7] K. Ahuja, T. Gupta, S. Ifthekar, S. Mittal, G. Yadav, and P. Kandwal. Variability in management practices and surgical decision making in spinal tuberculosis: An expert survey-based study. Asian Spine J., 16(1):9–19, 2022.
[8] W. Li, Z. Liu, X. Xiao, Z. Zhang, and X. Wang. Comparison of anterior transthoracic debridement and fusion with posterior transpedicular debridement and fusion in the treatment of mid-thoracic spinal tuberculosis in adults. BMC Musculoskelet Disord, 20(1):570, 2019.
[9] DX Zou, JL Zhou, XX Zhou, and XB Jiang. Clinical efficacy of ct-guided percutaneous huge ilio-psoas abscesses drainage combined with posterior approach surgery for the management of dorsal and lumbar spinal tuberculosis in adults. Orthopaedics & Traumatology: Surgery & Research, 103(8):1251–1255, 2017.
[10] Haopeng Luan, Qiang Deng, Weibin Sheng, Mardan Mamat, Hailong Guo, and Huaqiang Li. Analysis of the therapeutic effects of staged posterior–anterior combined surgery for cervicothoracic segmental tuberculosis with kyphosis in pediatric patients. International Journal of General Medicine, pages 4847–4855, 2021.
[11] Zhenchao Xu, Zhen Zhang, Xiyang Wang, Yilu Zhang, and Yunqi Wu. Medium-term follow-up outcomes of one-stage posterior lumbosacral or lumbopelvic fixation in the management of lumbosacral junction tuberculosis in adults. Orthopaedic Surgery, 13(7):2051–2060, 2021.
[12] H. Zhang, Q. Guo, S. Liu, C. Guo, Q. Gao, and M. Tang. Comparison of mid-term outcomes of posterior or postero-anterior approach using different bone grafting in children with lumbar tuberculosis. Medicine (Baltimore), 98(10):e14760, 2019.
[13] H. Zhang, Q. Guo, C. Guo, J. Wu, J. Liu, Q. Gao, and Y. Wang. A medium-term follow-up of adult lumbar tuberculosis treating with 3 surgical approaches. Medicine (Baltimore), 96(45):e8574, 2017.
[14] Zhenchao Xu, Xiyang Wang, Zhen Zhang, Dingyu Jiang, Runze Jia, and Yilu Zhang. A comparison of three bone graft struts for interbody fusion using a posterior approach for lower lumbar spinal tuberculosis in adults: a midterm follow-up study. BMC Musculoskeletal Disorders, 23(1):590, 2022.
[15] Khaled Omran, Ahmed S Abdel-Fattah, Ahmed Othman, Ahmed O Youssef, Amr Solimen, Mohamed A ElRefai, Ahmed N Saleh, and Mohammed Ali. Lateral extracavitary approach versus posterior extensive circumferential decompression in the treatment of complicated thoracic and lumbar tuberculous spondylitis. Clinical Spine Surgery, 30(9):E1211–E1219, 2017.
[16] D. N. Afonin, P. N. Afonin, P. I. Begun, and G. N. Pakhar’kov. Osobennosti razvitiia kompressii spinnogo mozga, nevrologicheskogo statusa i kachestva zhizni bol’nykh poliorgannym tuberkulezom. Klin Med (Mosk), 79(3):50–52, 2001.
[17] Kin Cheung Mak and Kenneth MC Cheung. Surgical treatment of acute tb spondylitis: indications and outcomes. European Spine Journal, 22:603–611, 2013.
Publication date:
10/22/2026
Facebook
LinkedIn
Mendeley
Reddit
Email